IHEP is rebuilding around a single, decisive thesis: accelerate HIV cure research by giving patients in Miami-Dade County the digital infrastructure they need to remain in care, sustain viral suppression, and contribute longitudinal biomarker data to the scientists working toward a cure.
We have deliberately restructured IHEP to do one thing exceptionally well, in one place, with one academic partner, before we attempt anything else. The previous multi-condition, multi-state, four-domain platform thesis has been retired in favor of a focused HIV-cure-research program governed by the University of Miami’s Human Research Protection Program.
What we are. A clinically governed digital health research organization developing patient-sovereign infrastructure for HIV retention, viral suppression, and cure-research data capture. Our work is anchored in Miami-Dade County, where the unmet need is greatest in the United States.
What we are not. A multi-condition platform. A multi-state telehealth company. A direct-to-consumer wellness app. A vendor of unverifiable security guarantees or implausible clinical effect sizes. We have publicly retracted three claims that did not survive rigorous internal review.
What changed. A formal feasibility analysis confirmed that the path most likely to produce real outcomes for real patients is the narrowest path: HIV-only, Miami-Dade-anchored, clinical-twin-only, IRB-governed, and partnered with the University of Miami from day one.
How we measure success. Time-to-viral-suppression in newly diagnosed patients. Sustained suppression at twelve and twenty-four months among engaged users. Longitudinal biomarker capture available to UM cure-research investigators. Retention-in-care rates benchmarked against published Ryan White Part A Miami-Dade cohort data.
What we will not do. Promise outcomes that exceed published RCT effect sizes. Operate human subjects research without IRB authority. Process protected health information outside a governed business-associate framework.
Every component of the IHEP platform now serves one of three clearly defined research pillars. Anything that does not fit one of these pillars has been deferred or retired.
Care-coordination and appointment-adherence tooling designed for the population most affected in Miami-Dade. Our retention model is built around the operational realities of Ryan White Part A clinical sites, not around generalized telehealth assumptions.
We target a 10 to 15 percentage-point absolute improvement in twelve-month viral suppression among engaged users, consistent with published mHealth research. Higher-engagement subgroups may exceed this; we will not promise what the literature does not support.
Patient-consented, IRB-governed, biomarker-and-outcome capture structured for the requirements of HIV cure investigators. The platform is not the science. The platform exists to make the science more tractable.
Mosca’s inequality formalizes when an organization must begin migrating to post-quantum cryptography. For HIV-related health information, the inequality is not close. It is decisive.
We have right-sized our PQC posture: hybrid ML-KEM-768 post-quantum TLS from day one, ML-DSA signatures for long-lived artifacts, and crypto-agile key management. We retain the technical aggressiveness of our prior architecture while removing budgetary excess that did not serve patients.
IHEP is structured to operate as a research industry partner of the University of Miami, with the Human Subjects Research Office serving as the IRB of record for all human subjects research conducted under our protocols. This is not a marketing relationship. It is the governance backbone of the program.
We have submitted a formal letter of introduction to the UM Human Subjects Research Office proposing the structure below. Our clinical physician investigator, a Miller School alumnus, anchors the protocol at the institutional level.
The composition of our founding team has been shaped by the requirements of the University of Miami partnership: a principal investigator, an assistant principal investigator, a system architect, and a clinical physician investigator with established Miller School credentials.
Founder · Evolution Strategist
Director · Co-Investigator
Technical Lead · DIESEL Collective
Physician · Psychiatrist · UM Miller School Alumnus
No human subjects research occurs before IRB authority is in place. No protected health information flows before agreements are executed. Each gate has a date.
Inquiries from academic medical centers, Ryan White grantees, HIV cure-research investigators, and aligned funders are welcomed.
partnerships@ihep.app